Definity/Optison

Numerous reports of serious adverse reactions including death have been linked to the micro-bubble contrast agents Definity and Optison. The drugs are used to enhance ultrasound images during echocardiography (ECG), a procedure that helps in the diagnosis of heart ailments. As of October 2007, both drugs will carry a black box warning on their label regarding the risk of potentially fatal cardiac reactions. The revised label also warns of:

• Loss of consciousness
• Convulsions
• Breathing difficulties
• Hypotension
• Cardiac arrhythmia
• And other life-threatening allergic reactions

If you or your loved one experienced a severe reaction to Definity or Optison, an experienced attorney can help you understand your legal rights. Click here to arrange a free consultation.

Reports of Death, Other Reactions
The Food and Drug Administration approved Definity in 2001, and most of the adverse reactions reported to the agency involve this drug, not Optison. According to the FDA, 10 deaths and 190 non-fatal reactions were reported in association with Definity. Many of the adverse events occurred within 30 minutes of the drug’s administration.

Optison gained FDA approval in 1997 but was removed from the market in 2005. It is associated with one death and nine non-fatal reactions.

At Risk Patients
Many of the patients who suffered a fatality had a serious underlying condition. The following conditions may increase the risk of a severe reaction during or after the administration of a micro-bubble contrast agent like Definity or Optison:

• Unstable angina
• Congestive heart failure
• Severe emphysema
• Respiratory failure
• Blood clots
• Heart arrhythmias
• Cardiac shunts

Contact an Attorney Today
Patients trust that the drugs they are given will help—not harm—them, and drug makers are obligated to ensure the safety of their products. If you or your loved one suffered harm because of Definity or Optison, you may be able to hold the drug’s maker legally responsible for your damages.

To learn more about your legal rights, contact us today and discuss your case free of charge with an experienced product liability attorney.